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TRP Channel


TRP channels (Transient receptor potential channels) are a group of ion channels located mostly on the plasma membrane of numerous animal cell types. There are about 28 TRP channels that share some structural similarity to each other. These are grouped into two broad groups: Group 1 includes TRPC,TRPV,TRPM,TRPN, and TRPA. In group 2, there are TRPP ,and TRPML. Many of these channels mediate a variety of sensations like the sensations of pain, hotness, warmth or coldness, different kinds of tastes, pressure, and vision. TRPs have been seen to have complex multidimensional roles in sensory signaling. Many TRPs function as intracellular calcium release channels.

  • DIDS EI0978

    DIDS是氯离子（Cl）通道阻断剂， TRPV1 调节剂， RAD51 recombinase 抑制剂。

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  • DH 97 EI0970

    DH 97是MT2 受体拮抗剂。

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  • CIM 0216 EI0799

    CIM 0216是选择性 TRPM3 激动剂。

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  • ASP 7663 EI0495

    ASP 7663是选择性 TRPA1 激动剂。

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  • Arvanil EI0488

    Arvanil是活性的 CB1 和 TRPV1 激动剂。 也是anandamide 转运抑制剂。

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